IVF failure is a huge blow to any couple.
However, the truth is that a failed first IVF does not necessarily indicate a failure of the second.
Many couples are able to succeed easily with a second or third IVF –
provided the correct cause is identified and the next IVF is planned accordingly.
In this blog, you will learn:
✔ Why did your first IVF fail?
✔ How to plan your second IVF correctly?
✔ How can you increase the success rate of Shradha IVF?
⭐ 1️⃣ Why did the first IVF fail? Finding the root cause is crucial.
Often, the reason for IVF failure is not disclosed.
But understanding the root cause is the most important step toward a successful IVF.
The main reasons for IVF failure are:
🔹1. Decrease in Egg Quality (Age Factor)
Egg quality naturally decreases at the age of 35+.
🔹 2. Poor sperm quality (DNA damage)
Even seemingly “normal” semen reports are sometimes misleading.
🔹 3. Weak embryo quality:
IVF is successful only when the embryo is chromosomally correct.
🔹 4. Weak or inflamed lining of the uterus.
Thin lining, adenomyosis or chronic infection prevents implantation.
🔹 5. Hormone imbalance
Thyroid, prolactin, insulin – These have a direct impact on the success of IVF.
🔹 6. APLA / Blood clotting issues
These disturb the pregnancy in the initial weeks by blocking the blood supply to the embryo.
🔹 7. IVF protocol mismatch:
If the stimulation protocol is not correct, eggs are not obtained properly.
👉 Finding out the real reason for failure before the second IVF determines 50% success.
⭐ 2️⃣ How to Make Your Second IVF Successful? – 10 Steps
At Shradha IVF, we plan every second IVF cycle as “Precision IVF”.
✔ Step 1: “Failure Analysis Test Panel”
This complete checkup is mandatory before the second IVF:
Hormone profile
AMH, AFC scan
Thyroid, prolactin
Sugar & insulin
Semen DNA Fragmentation
Uterus lining test + 3D Scan
Chronic endometritis (CD138 biopsy)
APLA/Thrombophilia (blood clotting tendency)
Vitamin levels
Infection profile
These tests tell how to plan IVF this time.
✔ Step 2: Egg Quality Boost Program (4–6 weeks)
In case of age 35+ or first IVF failure, we increase the strength of the follicle by including
CoQ10, lifestyle correction, sleep, diet, exercise – all of these.
✔ Step 3: Sperm Quality Optimization
Shradha IVF uses the latest AI-based semen analysis (LensHooke).
Where needed:
The best sperm are selected using the MACS
PICSI
Microfluidic chip . ✔ Step 4: Choosing the Right IVF Stimulation Protocol A new protocol is developed based on data from previous IVF procedures:
antagonist protocol
long protocol
dual trigger
higher gonadotropin dose
estrogen priming
luteal phase stimulation
Every woman’s body is different—so the protocol should be different too.
✔ Step 5: Embryo formation in the safest way (ICSI + AI Monitoring)
in the high-grade embryology lab at Shradha IVF:
ICSI
Laser assisted hatching
Time-lapse evaluation
AI-based embryo grading
is used.
✔ Step 6: PGT-A (Genetic Testing) – If the first IVF failed without any reason,
Age 35+, recurrent IVF failure or miscarriage,
PGT-A is the best option.
It only helps in selecting “normal embryo”.
✔ Step 7: Uterus की Lining को Perfect बनाना
IVF only works if uterus is ready.
We do:
PRP therapy
G-CSF therapy
lining thickening protocol
hysteroscopy for septum, polyp, adhesion
chronic infection treatment
✔ Step 8: Frozen Cycle (FET) is preferred
Fresh cycle has a lot of hormones.
Therefore, in second IVF, we mostly prefer Frozen Embryo Transfer.
This scientifically increases the success rate.
✔ Step 9: Choosing the Right Implantation Window
The exact time of implantation varies for some patients. We identify
this through ultrasound, hormone tracking, or endometrial evaluation if necessary .
✔ Step 10: Pregnancy Support & Monitoring (First 12–14 weeks)
This is the most crucial time for IVF success.
At Shradha IVF, we:
Regular hormone monitoring,
blood flow scans,
uterine artery Doppler,
clotting risk management,
personalized support plan.
This makes the first trimester of pregnancy safer.
🌼 Will a second IVF be successful? Yes—if done correctly.
A failed first IVF doesn’t mean you have any hope.
In fact, in a second IVF, we incorporate
👉 all the learnings from the first cycle
👉 complete scientific evaluation
👉 advanced embryo technology
👉 uterus preparation
👉 expert monitoring
All together, the potential for success is very high.
🌟 Why can your second IVF be successful at Shradha IVF & Maternity?
✔ MRCOG London–trained IVF specialist
✔ Bihar’s most advanced IVF setup
✔ AI-based sperm + embryo evaluation
✔ Global-standard embryology lab
✔ Precision-based treatment plan
✔ High success in second-cycle IVF
✔ Emotional + scientific counselling
✔ 14-week safe pregnancy follow-up plan
🌸 Final Message
The first IVF failure is not the end –
it’s just the first step to the next success.
Second IVF is often successful
because it takes into account all the reasons for the failure of the first IVF and
creates a scientific, personalized and safe plan.
At Shradha IVF, it is our responsibility to make your next pregnancy safe, successful, and happy.
