Medically Reviewed by Dr. Shradha Chakhaiyar, MBBS, DGO, MRCOG (London) — IVF Specialist & Reproductive Surgeon, Shradha IVF & Maternity, Patna
20+ Years of Experience · www.shradhaivf.com
Male infertility means a man’s ability to cause pregnancy is reduced, usually due to problems with sperm count, movement, or shape. It contributes to roughly 40–50% of all infertility cases. The most common treatable cause is a varicocele. Diagnosis starts with a simple semen analysis, and treatments range from lifestyle changes, medication, and surgery to IUI, IVF, and ICSI — which can help even with very low or zero sperm counts.
📋 What This Guide Covers
- What is male infertility?
- How common is it really?
- Signs and symptoms
- What causes male infertility
- How it’s diagnosed — start here
- Semen analysis: normal values
- Treatment by cause
- Zero sperm count: is there hope?
- ICSI — the game-changer
- Improving sperm health naturally
- The Bihar context
- A note from Dr. Shradha
- FAQs
What Is Male Infertility?
Male infertility is a reduced ability to cause a pregnancy in a fertile partner, usually after twelve months of regular, unprotected intercourse (six months if the female partner is over 35). In the great majority of cases, the issue comes down to sperm — too few, moving too poorly, shaped abnormally, or absent altogether — or to a problem with delivering that sperm. It is a medical condition, not a measure of masculinity, and like most medical conditions, it is treatable in the majority of cases.
The four main sperm problems have specific names you may see on a report:
- Oligospermia — low sperm count
- Asthenozoospermia — poor sperm movement (motility)
- Teratozoospermia — abnormal sperm shape (morphology)
- Azoospermia — no sperm in the ejaculate
How Common Is It Really?
Far more common than most people assume. Infertility affects roughly 10–20% of couples, and male factor contributes to about 40–50% of those cases — sometimes as the sole cause, sometimes alongside a female factor. In other words, in roughly half of all couples struggling to conceive, the man is part of the picture. This single fact should change how every couple approaches testing — and yet, culturally, it rarely does. We’ll come back to why that matters so much.
What are the Signs and Symptoms of Male Infertility
Here is an uncomfortable truth: male infertility usually has no obvious symptoms at all. Most men feel completely healthy, have a normal sex life, and have no idea anything is wrong until a couple struggles to conceive and a semen analysis is done. This is precisely why testing matters — you cannot feel a low sperm count.
When symptoms do appear, they may include difficulty conceiving, changes in sexual desire, pain or swelling in the testicle area (which can indicate a varicocele or infection), difficulty with erection or ejaculation, reduced facial or body hair (a possible sign of hormonal imbalance), or a low ejaculate volume. But their absence proves nothing — which is the whole point.
What Causes Male Infertility?
Causes fall into several groups. Importantly, many are treatable, and some are simply a matter of lifestyle. Here’s the landscape:
| Cause | What it is | Treatable? |
|---|---|---|
| Varicocele | Swollen veins in the scrotum that overheat the testicle — the most common cause, in 20–40% of infertile men | ✅ Often, with surgery |
| Infections | Epididymitis, orchitis, or STIs that impair sperm production or block delivery | ✅ Often, with antibiotics |
| Hormonal disorders | Problems in the pituitary, hypothalamus, or low testosterone affecting sperm production | ✅ Often, with hormone therapy |
| Lifestyle & environmental | Smoking, alcohol, heat, obesity, stress, pesticides, heavy metals | ✅ Yes — modifiable |
| Ejaculation problems | Retrograde ejaculation, erectile dysfunction, blockages | ✅ Often |
| Genetic conditions | Klinefelter syndrome, Y-chromosome microdeletion, cystic-fibrosis-related blockage | Sometimes (ART may help) |
| Medical treatments | Chemotherapy, radiation, some medications, surgery | Prevention (sperm freezing) where possible |
| Idiopathic (~30%) | No identifiable cause — often linked to oxidative stress | ✅ Often responds to antioxidants/ART |
The lifestyle and environmental factors deserve emphasis because they are within your control: smoking, excessive consumption of alcohol, obesity, chronic stress, heat (laptops on the lap, hot work environments, frequent saunas), and exposure to pesticides and heavy metals all reduce sperm count and quality. Each of these has its own detailed guide on our blog.
How Male Infertility Is Diagnosed — Start Here
This is the most important section in this article, so I’ll be blunt: the first test for any couple struggling to conceive should be a semen analysis for the man. It is simple, inexpensive, non-invasive, and gives an enormous amount of information in one go. It makes no medical sense to put a woman through months of invasive testing before a man has produced a single sample — and yet that is exactly what happens in most households, for reasons we’ll discuss below.
The full diagnostic toolkit, used as needed:
- Semen analysis — the primary first test; measures count, motility, morphology, and volume.
- Physical examination — checks for varicocele and testicular abnormalities.
- Hormonal profile — testosterone, FSH, LH and others when production is in question.
- Scrotal ultrasound — images the testicles and detects varicoceles or blockages.
- Sperm DNA fragmentation (DFI) — assesses the genetic integrity of sperm; valuable in unexplained cases or recurrent miscarriage (offered at Shradha IVF).
- Genetic testing — recommended when there is no sperm or a very low count, to identify conditions like Klinefelter syndrome or Y-microdeletion.
Semen Analysis: What Are the Normal Values?
If you’ve had a semen analysis, you’re probably staring at numbers you don’t understand. Here are the widely used World Health Organization reference values. A result below these doesn’t mean conception is impossible — it means the odds are reduced and worth addressing.
| Parameter | WHO reference (lower limit) | What it measures |
|---|---|---|
| Semen volume | ≥ 1.4–1.5 mL | Amount of fluid per ejaculate |
| Sperm concentration | ≥ 15–16 million / mL | Sperm density |
| Total sperm number | ≥ 39 million / ejaculate | Total sperm count |
| Total motility | ≥ 40–42% | % of sperm moving |
| Progressive motility | ≥ 30–32% | % moving forward effectively |
| Normal morphology | ≥ 4% | % of normally-shaped sperm |
| Vitality | ≥ 54–58% | % of live sperm |
Reference ranges vary slightly between WHO editions (2010 vs 2021) and between laboratories — always interpret your report with your fertility specialist, not in isolation. A single below-normal result should also be repeated, as samples vary. For more on shape and movement specifically, see our guide to sperm abnormalities.
Male Infertility Treatment by Cause
Because male infertility has many causes, treatment is matched to the cause — which is why an accurate diagnosis matters so much. The main pathways:
| Approach | Used for |
|---|---|
| Lifestyle changes | First-line for everyone — stop smoking, reduce alcohol, lose excess weight, avoid heat, manage stress, improve diet |
| Medication | Antibiotics for infections; hormone therapy for hormonal causes; sometimes clomiphene to stimulate sperm production; antioxidants for oxidative stress |
| Surgery | Varicocele repair (varicocelectomy); correction of blockages; vasectomy reversal |
| Surgical sperm retrieval | TESA / TESE / micro-TESE — retrieving sperm directly from the testicle when there is none in the ejaculate |
| IUI | Mild male factor — prepared sperm placed directly in the uterus |
| IVF | Moderate male factor, or combined with a female factor |
| ICSI | Severe male factor — a single healthy sperm injected directly into the egg |
| Sperm freezing | Preserving fertility before chemotherapy, radiation, or certain surgeries |
“They Told Me I Have Zero Sperm Count” — Is There Still Hope?
Yes — and this is one of the most important things I want men to understand. A diagnosis of azoospermia (no sperm in the ejaculate) does not always mean no sperm at all. In many men, sperm are still being produced in the testicles but aren’t reaching the ejaculate, often because of a blockage. In these cases, sperm can frequently be retrieved directly from the testicle through a minor procedure (TESA, TESE, or micro-TESE) and then used to fertilise an egg through ICSI.
Even when production is very low, modern techniques often require only a small number of viable sperm. So a “zero” on a semen report is the beginning of an investigation, not the end of the road.
ICSI — The Game-Changer for Male Factor
If there is one development that transformed the outlook for male infertility, it is ICSI (Intracytoplasmic Sperm Injection). In conventional IVF, sperm and egg are placed together, and fertilisation is left to chance, which fails when sperm are too few or too weak to penetrate the egg. In ICSI, an embryologist selects a single healthy sperm and injects it directly into the egg under a microscope. This means that even men with extremely low counts, poor motility, or surgically retrieved sperm can father a biological child.
At Shradha IVF, ICSI is performed in our on-site embryology laboratory — so couples in Bihar no longer need to travel to Delhi or Mumbai for advanced male-factor treatment.
Improving Sperm Health Naturally
Because sperm take about 70–90 days to develop, lifestyle changes made today show up in a semen analysis two to three months later. The evidence-based steps:
- Stop smoking and limit alcohol — both directly damage sperm count and DNA.
- Eat well — an antioxidant-rich diet supports sperm quality; correct folate, vitamin D, and zinc deficiencies.
- Reach a healthy weight — obesity disrupts the hormones that drive sperm production.
- Keep cool — avoid laptops on the lap, prolonged heat, and very hot baths; the testicles work best slightly below body temperature.
- Manage stress — chronic stress affects the hormones behind sperm production.
- Reduce toxin exposure — minimise contact with pesticides and heavy metals where possible.
Why Men Get Infertility Test Too Late in India?
I have to be honest about something I see every week. In Bihar, when a couple cannot conceive, the assumption — from family, from neighbours, sometimes from doctors — is almost always that the problem lies with the woman. She is examined, investigated, and treated, often for a year or more, before anyone suggests her husband produce a sample. This is not just unfair; it is medically backwards, because male factor is involved in roughly half of cases and the man’s test is the easiest one to do.
There are also genuine local risk factors worth naming: agricultural pesticide exposure in farming communities can impair sperm quality; nutritional deficiencies — folate, vitamin D, and zinc — are common in local diets and affect sperm; and occupational heat and pollution add to the load. None of this is a cause for shame. It is simply biology, and almost all of it is testable and treatable. My request to every couple is the same: get tested together, from the start.
A Note from Dr. Shradha, Patna
At Shradha IVF & Maternity, both partners are evaluated together from the first visit, with an on-site embryology laboratory, ICSI capability, and sperm DNA fragmentation testing — all under the personal care of Dr. Shradha Chakhaiyar, MRCOG (London). The first consultation is free.
The First Test Is the Simplest. Take It Together.
Male infertility is common, usually treatable, and nothing to be ashamed of. A semen analysis and a conversation with Dr. Shradha can give you real answers — and a clear, honest plan. Both partners are evaluated together, and the first consultation is free.
FAQs on Male Infertility
Male infertility means a man's ability to cause pregnancy is reduced, usually due to problems with sperm count, movement (motility), or shape (morphology), or with delivering sperm. It's diagnosed after a couple has tried to conceive for 12 months (6 if the woman is over 35) and is treatable in most cases.
Male factor contributes to roughly 40–50% of all infertility cases — sometimes as the only cause, sometimes alongside a female factor. In other words, in about half of couples struggling to conceive, the man is part of the picture, which is why both partners should always be tested together.
Usually there are none — most men feel perfectly healthy and only discover a problem through a semen analysis. When symptoms appear they may include testicular pain or swelling, changes in sexual desire or erection, low ejaculate volume, or reduced body hair. The absence of symptoms does not rule out infertility.
The most common treatable cause is a varicocele (swollen scrotal veins). Others include infections, hormonal disorders, genetic conditions, blockages, and medical treatments like chemotherapy. Lifestyle and environmental factors — smoking, alcohol, obesity, heat, stress, and pesticides — also play a large role. About 30% of cases have no identifiable cause.
Widely used WHO reference values are: volume ≥1.4–1.5 mL, sperm concentration ≥15–16 million/mL, total count ≥39 million per ejaculate, total motility ≥40%, progressive motility ≥30%, and normal morphology ≥4%. Values vary by lab and WHO edition, and a below-normal result should be repeated and interpreted by a specialist.

